Chemistry in the Institute for Single Crystals
From the first day of its foundation the chemistry studies there carried out in such scientific fields as chemistry of luminophors and dyes (Prof. Boris Krasovitskiy), design of liquid-crystal composites, raw material synthesis and purification techniques for crystal growth, analytical chemistry and structure studies of functional materials (Prof. Avram Blank).
In the field of the design of new organic luminophors and dyes Prof. Boris Krasovitskiy started at SSI ISC the synthesis and research of perspective organic luminescent compounds. Prof. Krasovitskiy monograph “Organic luminophors” published in 1972 has received several editions and became all-known the world. Later the scientific interests also involved the search for new functional materials including laser dyes, markers and probes for biomedical studies.
Liquid-crystals (LC) was one the main topics at the SSI ISC, supervised by Prof. Lidiya Kutulya. In the 70’s there was developed a number of LC-thermoindicators for industry and domestic use. In the 90’s the search was focused on bioequivalent detectors of irradiation and converters of light and solar energy.
Analytical chemistry in SSI “Institute for Single Crystals” was conducted with the development of analytical techniques for determination of trace amounts of impurities in raw materials for growing single crystals and environmental objects.
Division of Functional Materials Chemistry
In 2005, to improve the Chemistry studies at the SSI Institute for Single Crystals, there was established the Division of Functional Materials Chemistry with 5 research departments as a part of SSI ISC and today it involves 3 additional laboratories:
- Department of X-ray Diffraction Studies and Quantum Chemistry with
- Ukrainian-American Laboratory of Computational Chemistry
- Department of Organic and Bioorganic Chemistry with
- Laboratory of Physicochemical Processes
- Medicinal Chemistry Team
- Department of Technology of Organic Materials
- Department of Organic Luminophores and Dyes
- Department of Analytical Chemistry
- Laboratory of Technology and Analysis of Drugs
Main scientific areas of the Division are the following:
Computational Chemistry and Chemical Crystallography. Structure, conformational analysis and intramolecular interactions of organic compounds. Crystal
structure and properties of inorganic materials and thin films. Conjugation and hyperconjugation in cyclic systems. Weak intermolecular interactions. Molecular modelling and design.
Organic Chemistry. Theoretical aspects of heterocyclic compounds chemistry. Synthesis, properties and modification of nitrogen-, oxygen- and sulfur-containing heterocycles. Development and study of supramolecular compounds and nano-scale materials. Application of non-classical methods of activation (microwave and ultrasonic
irradiation) for chemical synthesis and fundamental studies of the physicochemical aspects of interaction of microwave irradiation with matter. Synthesis of chiral organic compounds as the component to liquid crystalline systems.
Inorganic Chemistry. Microwave assisted and classical inorganic synthesis of pure inorganic compounds.
Functional Material Science. Fluorescence-based materials for the life sciences. Probes and labels for biomedical applications. Materials for flow detection. Organic scintillation materials. Organic fluorescent colorants. UV-Vis-NIR steady-state and fluorescence lifetime (FLT) spectroscopy. Molecular structures and conformation isomerism and properties of chiral dopants for liquid crystals. Twisting properties of chiral nonlinear electromechanical processes in ferroelectric liquid crystals. Composite materials on the base of magnetic nanoparticles and especially designed organic medium.
Analytical Chemistry of functional materials, noble metals, environmental objects, foodstuffs, medicines. X-ray, atomic-emission, atomic-absorption and molecular spectrometry. Express-tests for detection and semi-quantitative analysis of toxic and biologically active substances. Sample preparation. Qualitative and quantitative analysis of organic mixtures with the use of GC-MS, GC and HPLC techniques.
Medicinal Chemistry. Drug design. Molecular docking. Directed synthesis of biologically active compounds and API.
Microwave Equipment and Technologies. Development of unique microwave equipment for laboratories, chemical, pharmaceutical and other types of industry. Novel technologies for drying, sterilization, cleaning and evaporation.
International activities of our Division include participation in international projects and academic exchange programs with scientific groups worldwide.