Division of Functional Materials Chemistry
State Scientific Institution “Institute for Single Crystals”
of National Academy of Sciences of Ukraine

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Selected publications

Regulatory Documents

  1. Ministry of Health of Ukraine Regulation ST-N MOHU 42-4.9:2020. Medicinal Products. Guidance on Good Manufacturing Practice specific to Advanced Therapy Medicinal Products. Bezugla O., Lyapunov M., Isaenko P., Tahtaulova N. Kyiv, MoH of Ukraine, 2020, 88 p. (In Ukrainian)

  2. Ministry of Health of Ukraine Regulation ST-N MOHU 42-4.0:2020. Medicinal Products. Good Manufacturing Practice. Lyapunov M., Bezugla O., Tahtaulova N. et al. Kyiv, MoH of Ukraine, 2020, 278 p. (In Ukrainian)

  3. Ministry of Health of Ukraine Regulation ST-N MOHU 42-3.9:2014. Medicinal Products. Impurities in New Drug Substances and New Drug Products. Lyapunov M., Antipova O., Baula O. et al. Kyiv, MoH of Ukraine, 2014, 34 p. (In Ukrainian)

  4. Ministry of Health of Ukraine Regulation ST-N MOHU 42-5.0:2014. Medicinal Products. Good Distribution Practice. Lyapunov M., Bezugla O., Pasichnyk M. et al. Kyiv, MoH of Ukraine, 2014, 51 p. (In Ukrainian)

  5. Ministry of Health of Ukraine Regulation ST-N MOHU 42-3.8:2013. Medicinal Products. Pharmaceutical Quality of Inhalation And Nasal Products. Bezugla O., Lyapunov M., Solov`yov O. Kyiv, MoH of Ukraine, 2013, 52 p. (In Ukrainian)

  6. Ministry of Health of Ukraine Regulation ST-N MOHU 42-3.0:2011. Medicinal Products. Pharmaceutical development (ICH Q8). Lyapunov M., Bezugla O., Pidpruzhnykov Yu. et al. Standardization of pharmaceutical products, Kyiv, MoH of Ukraine, 2012, 19-56. (In Ukrainian)

Original articles

  1. Bezugla O.P., Krasnopyorova A.P., Liapunova A.M., Yukhno G.D., Lyapunov M.O. Study of viscosity and quasi-thermodynamic activation parameters for viscous flow in the system water-(propylene glycol-macrogol 400), Funct. Mater., 2023, 30 (1), 60-64.

  2. Bezugla O., Krasnopyorova A., Liapunova A., Zinchenko I., Lyapunov N., Sytnik O. Influence of physicochemical properties and structure of mixed solvents propylene glycol – macrogol 400 on their in vitro release., ScienceRise. Pharm. sci., 2023, 1(41), 4-13.

  3. Bezugla O., Liapunova A., Zinchenko I., Liapunov O., Lyapunov N., Stolper Y. Study of factors affecting the in vitro release of ketoprofen from carbomers-based gels, ScienceRise. Pharm. sci., 2022, 6(40), 4-20.

  4. Lyapunov N., Bezugla O., Liapunova A., Zinchenko I., Liapunov O., Lysokobylka O., Stolper Y. Effect of the composition of emulsifiers and the dispersion medium on the properties of bases for semi-solid preparations, ScienceRise. Pharm. sci., 2022, 5 (39), 29-45.

  5. Bezugla O., Lyapunov N., Chebanov V., Liapunov O. Study of the formation of micelles and their structure by the spin probe method, ScienceRise. Pharm. sci., 2022, 4 (38), 4-18.

  6. Bezugla O.P., Lyapunov M.O., Zinchenko I.O., Lisokobilka O.A., Liapunova A.M. Modeling of processes of solvent diffusion from ointment bases using in vitro experiments, Funct. Mater. 2022, 29 (4), 553-558.

  7. Bezuglaya E., Lyapunov N., Bovtenko V., Zinchenko I., Stolper Y. Study of pressurised metered dose inhalers for the purpose of standardization of quality attributes characterizing uniformity of dosing, ScienceRise. Pharm. sci., 2021, 4 (32), 11-23.

  8. Bezuglaya, E., Zinchenko, I., Lyapunov, N., Vlasenko, H., Musatov, V. Substantiation of an approach to determination of ketoprofen macro-gel 400 esters. ScienceRise. Pharm. sci., 2021, 3 (31), 51-63.